Chronotherapy: can our biological clock help heal us?

Chronotherapy: can our biological clock help heal us?

Nevertheless, in general, “we are still challenged to put into practice in the medical world this knowledge on the role of circadian clocks“, warned last year the researchers Ravi Allada and Joseph Bass, in an inventory published in the New England Journal of Medicine.

There is therefore a lack of techniques that would allow a doctor to easily diagnose a disruption of the biological clock and, therefore, to advise a patient in a targeted manner to change his rhythm of life in order to avoid health problems.

Other avenues risk colliding with reality, such as the idea, certainly defended with enthusiasm by Claude Gronfier, of taking into account the time of day to administer chemotherapy to a cancer patient.

Imagine that a trial demonstrates that the treatment must be administered between 10 p.m. and 8 a.m.: that will pose small organizational problems“, the chemo being given under infusion at the hospital, warns AFP oncologist Pierre Saintigny.

We already live in a world, at least in France, where the health system is on the verge of collapse“, he continues. “You would really have to be very convincing to drastically change an organization where there is already enormous pressure.

It is therefore necessary not only that an effect be proven, but that it “has a major impact on treatment response and patient survival“, concludes Mr. Saintigny, considering that studies are currently insufficient in this area.

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