diabetes drug efficiently examined for weight reduction

In a double-blind, randomized, placebo-controlled Section 3 medical trial, researchers requested overweight adolescents aged 12 to 17 to obtain a weekly injection of two.4 mg of semaglutide, a drug prescribed to deal with diabetes, for 68 weeks. On the finish of this medical trial, the youngsters handled with this drug, misplaced on common 15% of their preliminary weight, that’s to say roughly 17 kilos.

Of the 201 adolescents enrolled within the trial, 133 had been handled with semaglutide (marketed in France underneath the title Ozempic®), whereas 67 obtained a placebo. Additionally they obtained diet recommendation and a bodily exercise program. Within the placebo group, the youngsters continued to realize weight: 3% of their preliminary weight on common, or about 2.5 kilos. Whereas within the group that examined the anti-diabetic, 73% of adolescents misplaced no less than 5% of their weight, 62% misplaced no less than 10% and 37% misplaced no less than 20%.

A slight weight acquire after the remedy

“The imply change in physique mass index (BMI) between week 1 and week 68 is -16.1% with semaglutide and 0.6% with placebo” underline the researchers, whose research simply revealed within the New England journal of drugs.

Nonetheless, the researchers observe that in a follow-up of seven weeks after remedy, some adolescents regained some weight, (…)

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