The “French intestine” undertaking scrutinizes the microbiota

The “French intestine” undertaking scrutinizes the microbiota

It’s a undertaking that its designers like to explain as” a little bit loopy “. It’s in any case bold since it’s a query, by 2027, of gathering, sequencing and analyzing the microbiota of 100,000 French individuals, with the purpose of mapping all their range.

In recent times, advances in genetic sequencing strategies have made it doable to advance within the information of what’s nonetheless typically known as the “intestinal flora”.

However research have up to now solely centered on a small variety of individuals, typically within the context of analysis into pathologies. Nevertheless, this ecosystem, made up of fifty,000 billion micro organism (i.e. 1 kg per particular person!), could be very completely different from one particular person to a different.

Measuring the impression of microbiota on well being

“At the moment, we all know that the microbiota performs an vital position in our digestive, metabolic, immune, neurological, recollects Thomas Lombès, Deputy Director Basic for Technique on the Nationwide Institute for Well being and Medical Analysis (Inserm), one of many 4 public establishments concerned on this undertaking led by the Nationwide Analysis Institute for Agriculture , meals and the atmosphere (Inrae), with the help of a dozen non-public companions. We additionally know that its alteration is a proof for a lot of pathologies, corresponding to weight problems, diabetes, Crohn’s illness or sure cancers. However we nonetheless have loads to know in an effort to exactly measure its impression on our well being.he defined throughout the official launch on September 15.

What position do weight-reduction plan, air pollution, stress or antibiotics play on this inside world? To what extent can we act on its composition to forestall the looks of sure ailments? These are a few of the questions the researchers hope to reply.

A worldwide microbiota database

Known as “Le French Intestine”, the undertaking is a part of an enormous worldwide program, “Million Microbiome of People Venture”, which plans to investigate a million faecal samples in an effort to represent the most important international database on the microbiota. .

On the French facet, the time has come to recruit volunteers, by way of a selected web site (1). Earlier than receiving a stool assortment package, every candidate must full a fifteen-minute questionnaire, scanning their consuming habits and way of life (smoking, sports activities actions, and so forth.). Among the many choice standards: being over 18, residing in metropolitan France, or not having taken antibiotics for 3 months.

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