The intestinal microbiota of the French
In recent times, research have demonstrated the elemental significance of the intestinal microbiota within the correct functioning of the physique and never solely of the digestive system. Microbiota imbalances are regarded as concerned within the improvement of assorted continual pathologies. To advance analysis on this area, INRAE is launching a nationwide undertaking, referred to as french intestineinviting each French particular person to take part with the intention to be taught concerning the microbiota of the French inhabitants.
What’s the intestine microbiota?
The intestinal microbiota, previously referred to as the intestinal flora, corresponds to the trillions of microorganisms that reside within the intestines, in symbiosis with the physique. In observe, the microbiota microorganisms – as a result of it’s not simply the intestinal microbiota but in addition the oral microbiota or the vaginal microbiota – are extra quite a few than all of the cells that make up the human physique.
Within the intestinal microbiota, there are micro organism, viruses and even yeasts (microscopic fungi). Every human being has his or her personal microbiota, though round a 3rd of the microbiota can be frequent to all human beings. The microbiota and its specificities are shaped from beginning (particularly on the time of contact with the mom’s vaginal and intestinal microbiota) and till the age of two or 3 years. The microbiota usually evolves little in maturity, however will be unbalanced or disturbed by a number of components:
- Taking medicine and particularly antibiotic medicine;
- The prevalence of sure pathologies.
Intestine microbiota and well being
The intestinal microbiota performs important roles for the right functioning of the physique:
- It participates within the processes of digestion, for instance of the dietary fibers contained in meals;
- It protects the physique from pathogens that enter and colonize the intestines;
- It participates in lots of capabilities, equivalent to satiety, development, response to emphasize, ache, and so on.
Conversely, in case of microbiota imbalance, what scientists name dysbiosisthe physique is extra uncovered and extra delicate to sure illnesses, equivalent to continual inflammatory bowel illness (IBD) or weight problems. And a few research counsel a hyperlink between dysbiosis and neurodegenerative illnesses (Parkinson’s illness) or Alzheimer’s illness or neuropsychiatric illnesses equivalent to schizophrenia, bipolar dysfunction or melancholy.
The French Intestine undertaking
Data and preservation of the intestinal microbiota is subsequently of paramount significance. On this context, INRAE has simply launched the French Intestine undertakingwhose ambition is to map the intestinal microbiota of 100,000 French folks by 2027. The principle goal is to grasp the affect of sure environmental and way of life components on this microbiota and to research the affect of sure illnesses on the microbiota.
In the end, the outcomes of the French Intestine undertaking will make it potential to extend data of the intestinal microbiota and thus to suggest preventive vitamin customized for every French particular personwith the intention to protect its microbiota and subsequently its well being. This undertaking is a part of an enormous worldwide analysis program on the microbiota. To take part, each French particular person can go to the positioning. As soon as included within the examine, he can be requested to provide his stool for evaluation of his microbiota!
Estelle B., Physician of Pharmacy
– The French microbiota, the French intestine. microbiome-foundation.org. Accessed September 21, 2022.
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