The sudden and deleterious impact of grapefruit on antihypertensives

The sudden and deleterious impact of grapefruit on antihypertensives

None of this makes grapefruit growers snigger. Svetlana Farafonova/Adobe Inventory

HISTORY OF MEDICINE – In wanting to check the consequences of alcohol on an antihypertensive drug, Canadian researchers made a shocking discovery.

Science is like love: generally you discover what you were not searching for, and alcohol might help break the ice. On the finish of the Eighties, historical past doesn’t say if the pharmacologists of the College of Western Ontario, in Canada, discovered love. However they found an sudden enemy: grapefruit juice, able to singularly modifying the absorption of sure medicine…

For David G. Bailey and his group, it began on a Saturday night time that we are able to guess was watered down. The researchers wished to check on volunteers the consequences of alcohol on an antihypertensive drug, felodipine. However it was essential to make the members drink with out them understanding if the beverage contained alcohol or not. So the Canadian researchers went looking for a fruit juice able to masking the actual style of ethanol. “Grapefruit juice was chosen (…) after a take a look at carried out with all of the fruit juices from a home fridge”will they write…

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